Propofol MCQ quiz -Anesthesia drug

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What is the dose of Propofol during intubation?

Correct! Wrong!

Induction Dose For intubation Dose 1-2mg/kg

How much mg/ml present in 1% propofol?

Correct! Wrong!

To do this easily, simply add a zero to the percentage (i.e., 2% solution has 20 mg/mL, a 10% solution has 100 mg/ml)

What is the name of the Receptor activated direct by giving Propofol?

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Agonist of GABA in its receptor Direct activation of GABA Receptor Gamma-aminobutyric acid (GABA) is an amino acid that functions as the primary inhibitory neurotransmitter for the central nervous system (CNS). It functions to reduce neuronal excitability by inhibiting nerve transmission.

Propofol will cause _____

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Propofol will cause Respiratory depression and large doses like an induction dose of propofol will cause apnea.

Propofol is a choice for ____

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Propofol is a useful and safe anesthetic drug in the management of malignant hyperthermia patients. Because it does not trigger malignant Hyperthermia.

Propofol will decrease the incidence of ____

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Propofol may produce its antiemetic effect by depleting the area postrema of serotonin as well as by a direct gamma-aminobutyric acid-mediated inhibition. propofol has a depressant effects on the chemoreceptor trigger zone(CTZ). This is center for stimulation of nausea and vomiting.

Propofol infusion syndrome is stimulated by?

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High dose and long duration of propofol infusion (maximum dose should be 28mL/hr (for a 70kg adult, 1% propofol at maximum of 4mg/kg/hr) will cause propofol infusion syndrome The syndrome presents as metabolic acidosis, hyperkalemia, hyperlipidemia, and rhabdomyolysis and may proceed to renal and cardiac failure and ultimately death.

Propofol is the drug of Choice in

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Along with opioids (alfentanil or remifentanil) propofol is the agent of choice for total intravenous anaesthesia (TIVA)

Propofol is highly protein bound and is metabolized in ______

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Propofol is highly protein bound (97%) and is metabolized in liver.

Propofol inducing pain on injection because it's____

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It is oil based preparation containing soyabean oil, egg lecithin and glycerol. As it contains oil so injection is painful and should be preceded or mixed with lignocaine.

Propofol once opened should be used within ___hrs

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Egg is a good media for bacterial growth. So It is mandatory to use propofol within 6hrs after opening.

Propofol will Reduce the Intraocular pressure. True or False

Correct! Wrong!

Propofol will Reduce the Intraocular pressure

Intracranial pressure will increase after propofol. True or False

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Propofol will decrease ICP (Intracranial pressure) and propofol is a effective brain protection drug.

Propofol does not contain ____

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Propofol contains- Soybean oil Egg lecithin Disodium edetate / metabisulfite as a preservative

Propofol onsite of Action___

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15-30 seconds (1 arm brain circulation).

Propofol is a___

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Propofol induces Bronchodilatation in COPD patients

Alternative for propofol is Fospropofol, and it's water based. True or False

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Fospropofol is a water soluble prodrug and is converted to propofol in the liver. Fospropofol is a short acting hypnotic sedative anesthetic agent. Unlike propofol, does not cause injection-site pain

Propofol is contraindicated for a patient who is allergic to ____

Correct! Wrong!

Propofol contains soybean oil

Rapid and smooth recovery makes propofol as the best anesthetic drug for Day care surgery. True or False

Correct! Wrong!

Rapid and smooth recovery makes propofol as the best anesthetic drug for Day care surgery

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Propofol will cause ___

Correct! Wrong!

propofol decreases systemic vascular resistance and is associated with hypotension during and after induction of anaesthesia.

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